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A number of the abnormalities mentioned above, such as proinflammatory consequences on the vessel wall, prothrombotic effects such as augmented platelet reactivity, decreased endogenous fibrinolysis, lipid peroxidation (LPO), and endothelial dysfunction, can all be explained by elevated oxidative stress (6769)

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However, Fonda and Hopper proved very quickly that they were actors more than filmmakers, as neither was able to top the success of Easy Rider behind the camera