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Those who took Pycnogenol (1 mg/kg daily) for 4 weeks showed significant improvement in attention, visual-motor coordination, and concentration , and reduced hyperactivity, compared to placebo

The answer depends on whether the vial is still lyophilized powder or has already been reconstituted into solution

J Agric Food Chem (2015) 63:361526

Functional characterization of DNA methylation in the oligodendrocyte lineage

10.1126/science.aaa5004 Science Summary Keywords vitamin C, ascorbic acid, SVCT2, radial glia cells, neurogenesis, neuronal differentiation, pluripotency, epigenetic reprogramming Citation Salazar K, Jara N, Ramrez E, de Lima I, Smith-Ghigliotto J, Muoz V, Ferrada L and Nualart F (2023) Role of vitamin C and SVCT2 in neurogenesis