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Peptide therapy uses targeted amino-acid sequences that mimic or influence natural hormones and growth factors in the body, delivered most often by subcutaneous injections, occasionally by oral or other routes depending on the molecule

134,320,321 It is observed to be upregulated in estrogen receptor-positive breast cancers and shows a positive correlation with estrogen receptor status

Moreover, upregulated expression of Lox family promoted the cross-linking of ECM components, suggesting the increased ECM stiffness (Fig

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(6) Lin N, Erdos T, Louie C, Desai R, Lin N, Ayzenberg G, Venketaraman V