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Another example involves esterase-degradable antimicrobial nanosponges, which are engineered by polymer-stabilizing self-assembled cationic poly(oxanorborneneimide) (PONI) scaffolds bearing guanidine, maleimide, and tetraethyleneglycol monomethyl ether (GMT) groups around essential-oil cores, followed by crosslinking with dithiol-disulfide (DTDS)

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Continuous outcome data, expressed as mean standard deviation (SD), were analyzed to calculate pooled effect sizes presented as standardized mean difference (SMD) with 95% confidence intervals (CI)

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Focusing on symptom profiles, only higher AES scores were linked to lower C2 ( = 0.05, SE = 0.02, p = 1.85e-2) and higher C3 ( = 0.08, SE = 0.02, p = 3.41e-5) levels