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This alteration results in the accumulation of toxic metabolites that can adversely affect renal function ( Table 1 ) [84, 85]

found that GHK-Cu cream improved skin laxity, clarity, and appearance, reduced fine lines and the depth of wrinkles and increased skin density and thickness when applied to facial skin for 12 weeks [14]

Oxidative Stress and the Microbiota-Gut-Brain Axis

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Researchers interested in skin-visible anti-aging effects tend to study GHK-Cu