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Despite causing an increased susceptibility to OS, G6PD deficiency may also protect against CVD, since NADPH is an essential cofactor for enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA R), and G6PD deficiency or NADPH deficiency may restrain HMG-CoA R activity similarly to statins (Fig

Neurexins-SS4+, a splicing variant containing exon 20 on the SS4 fragment, exhibits only weak adhesion and binding properties, and when exon 20 of SS4 is spliced, synapses exhibit strong adhesion and mutual binding [75, 76]

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When threats to homeostasis occur such as infection, hypoxia, and starvation (364, 365), they involve immune and inflammatory processes that influence energetics and metabolism (366, 367)

Glutathione fine-tunes the innate immune response toward antiviral pathways in a macrophage cell line independently of its antioxidant properties