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The reasons for this overall decline in usage among use are likely to be varied, but the CDC speculate that evidence-based tobacco use prevention strategies including price increases, smoke free policies and social media campaigns targeted at students of high school age have all made a difference

Journal of the American College of Cardiology, 43 , 17311737

Dual users of e-cigarettes and combustible cigarettes appear at even greater risk, with lower cardiorespiratory fitness and muscular endurance compared with non-users