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Primary endpoints should center on pain and function Knee Injury and Osteoarthritis Outcome Score (KOOS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Patient-Reported Outcome Measurement Information System (PROMIS) scores), structure (MRI evaluation with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) when appropriate), and time to milestones (return to sport)

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Although flavonoids are widely explored as multi-target natural metabolites in the pharmacological interventions for AD, some structurally reactive metabolites may function as pan-assay interference compounds (PAINS), thereby confounding mechanistic interpretation

Treatments may include a combination of medical treatments and home remedies

Our physicians and nurse practitioners will provide a free medical consultation and approve your treatment before you start the therapy