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NICE Clinical Knowledge Summaries recommend B12 injections for: Pernicious anaemia an autoimmune condition affecting intrinsic factor production Malabsorption syndromes including coeliac disease and inflammatory bowel disease Post-surgical states particularly following gastrectomy or ileal resection Strict vegan diets when oral supplementation proves inadequate, though oral cyanocobalamin is usually sufficient for dietary deficiency Clinical trials demonstrate that B12 injections rapidly improve haematological parameters and neurological symptoms when deficiency is confirmed through blood tests
Mechanistically, research on GHK-Cu by Mulder et al
Although there is currently no evidence to suggest any adverse side effects from excess vitamin B12 supplementation, there is no need to take excessively high amounts of the vitamin, as the body can only absorb so much anyway
"We have 10 years of supervised patient use." Yet other physicans urged the FDA committee to consider the lack of clinical evidence
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