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The goal in modern peptide science is to decouple the desired outcome (adiposity reduction) from off-target physiological noise (cardiovascular strain, insulin resistance, or neurological excitation)

These systems become more important as we age because NAD+ levels drop naturally

They might even trigger hypoglycemiaa potentially life-threatening condition where blood sugar drops too low

There is no official contraindication to using tirzepatide and sermorelin concurrently, but there is also limited clinical evidence specifically evaluating this combination

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