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Notably, the SOS study showed that in people with T2D, achieving and maintaining 15% WL over 15 years was associated with reductions in both micro- and macrovascular complications following BS [54]

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When the COX2 inhibition values were analyzed, IC 50 values in the range of 0.040.14 M were found, being comparable to celocoxib (0.05 M), where 20 , 24 , and 25 were more potent than the drug itself, used as a standard