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GHK-Cu in cosmetics (creams, rejuvenating serums) is allowed in the EU under the Cosmetic Regulation (EC 1223/2009), with aesthetic claims and application to the skin

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Symptoms of B12 deficiency include exhaustion no matter how much you sleep, muscle weakness and frequent cramping, constipation, loss of appetite and unexplained weight loss, numbness or tingling in the hands and feet, depression, and problems with memory and focus

There are other synthetic peptides that have not been well tested, often because early studies found they were not effective or are potentially toxic

Temperature-related errors Door storage exposes peptides to temperature swings with every refrigerator opening