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The GLP-1 Revolution: Beyond Diabetes and Obesity Semaglutide and tirzepatide have demonstrated efficacy across an expanding universe of indications that extends far beyond their initial diabetes approvals

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Kidney Dysfunction: In chronic kidney disease (CKD) or renal failure, the bodys ability to filter and excrete B12 may be compromised, leading to accumulation in the blood 8

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These effects are mediated by modulation of neurotransmitters (serotonergic, dopaminergic) and preservation of the blood-brain barrier