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a natural anti-arthritic agent) and CAT (Leo@CAT@NM-Lipo) was constructed, which catalysed high levels of ROS into oxygen and improved the low-oxygen microenvironment at the lesion site, thereby successfully decreasing arthritis scores, ameliorating paw swelling and bone and cartilage damage, and reversing multi-organ dysfunction in adjuvant arthritis (AA) rats

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Twenty-five milliliters of the test solution was then extracted by three-phase HF-LPME