Biological Activity NNMTi is a potent nicotinamide N-methyltransferase (NNMT) inhibitor (IC50=1.2 M), selectively binding to NNMT substrate binding site residues
de Rothschild, Paris, France, 4 INSERM U1266, Institut de Psychiatrie et Neurosciences de Paris (IPNP), Paris, France, 5 Division of Experimental Neurology, Department of Neurosciences, KU Leuven, Leuven, Belgium, 6 Department of Neurology, University Hospitals Leuven, Leuven, Belgium Background and Aims: Quantifying ischemic stroke lesions on acute-phase Diffusion-Weighted Imaging MRI (DWI) can guide treatment decisions
Huemer, ich mchte mich von Herzen bei Ihnen bedanken
[1] It tested once-weekly cagrilintide across a dose range and compared it with both placebo and an active comparator (liraglutide 3.0 mg)
Science 383 (6687), eadi7342