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Quantitative analysis of caspase-3 relative to -actin (Figure 7D) and the Bax/Bcl-2 ratio (Figure 7E) confirmed these observations, indicating a substantial reduction in apoptotic markers and an increase in anti-apoptotic markers in the GO@GSH-FA treatment group

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If an amino acid solution is treated with excess of neutralized formaldehyde solution , the amino group combines with formaldehyde forming dimethylol amino acid which is an amino acid formaldehyde complex

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In contrast to previous reports, the effect of these compounds appears to be independent of eryptosis, although their exact mode of action remains to be elucidated