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Current Opinion in Chemical Biology 33, 7480.Google ScholarPubMed Miller, EW, Lin, JY, Frady, EP, Steinbach, PA, Kristan, WB Jr and Tsien, RY (2012) Optically monitoring voltage in neurons by photo-induced electron transfer through molecular wires

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Reduced BDNF signaling may accelerate the degeneration of these neurons and impair the compensatory mechanisms that maintain motor function in early disease