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Raffa, M

However, the practical applications of most of these synthetic compounds remain restricted due to their limited administration routes, their narrow administration window for efficacy and their toxicity at high doses or during recurrent usage, making them far from ideal candidates for use by astronauts (172)

FerroLOXIN-1 and -2 both have been shown to inhibit ferroptotic death in the ileum and bone marrow, improve ileum integrity, and increase overall survival in irradiated mice [113, 115]

However, we are cautious with certain individuals

Figure 1 Because of the alteration of physiological or pathological conditions in the human body, the cellular copper content changes, resulting in the disturbance of copper homeostasis, namely, copper excess or copper deficiency