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The nanocomposite exhibited anti-AD efficacy by targeting hyperphosphorylated Tau, facilitating the monitoring of Tau retention using MRI/PET, reducing oxidative stress, and preventing hyperphosphorylated Tau aggregation, so providing effective Tau-targeted theranostics [42]

The research implications are substantial

The structural alignment revealed that GR24 5DS might cause steric hindrance with L142, L/F190, and F194 of the KAR-binding proteins ShHTL1, ShHTL3, and AtHTL (Supplementary Fig

Therapeutic targeting of immune-inhibitory and stimulatory pathways can alter the immune systems tolerance for self, resulting in damage to normal cells, known as immune-related adverse events (irAEs)