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Amyloid- and p-tau anti-threat response to herpes simplex virus 1 infection in primary adult murine hippocampal neurons

Sep Sci Technol 44(1):243262

Excessive levels of inflammatory proteins, such as C-reactive protein and some cytokines, have been reported in some studies in people with anxiety disorders, and inflammation may help sustain anxiety-related symptoms

These effects were mediated by activation of ERK1/2 in endothelial cells, as indicated by ERK inactivation leading to a decrease in these phenomena