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This is when dosing and frequency are adjusted

and spondylolisthesis (stress fractures causing the vertebrae to slip out of place) The same research suggests that these conditions can prevent the formation of new tissue (collagen) which can initiate repair

If your vitamin B12 deficiency is caused by a condition or medication that affects absorption, or your levels are very low, your GP may prescribe a course of vitamin B12 injections

Some ophthalmic trials extended treatment to 12 weeks at 4mg daily without safety issues

Routes reported in the literature include intraperitoneal, subcutaneous, intramuscular, intravenous, and oral administration