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It initially begins with insidious and uncharacteristic features, which makes the diagnosis process difficult

p = 0.037)

Recent CU can effectively alleviate liver cirrhosis (Zhang et al., 2024), alter the fecal microbiota composition in rats afflicted with liver fibrosis, reduce the abundance of Bacteroidetes, increase the abundance of Firmicutes and Proteobacteria, and inhibit the activity of TLR4/NF- signaling pathway, leading to reduced expression of inflammatory factors (IL-6, TNF-, IL-8) (Zheng et al., 2022)

Pair with a healthy lifestyle: Drink plenty of water to flush out toxins, use sunscreen daily to protect against sun damage, and eat a balanced diet rich in fruits and vegetables

Since the N-protective group is an amide, removal of this function might require conditions that would also cleave the just formed peptide bond