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One unsterilized injection introduces skin bacteria through the puncture

All other drugs with a positive effect in neurological symptoms in a preclinical trial in SCA3 rodent models (and which have not been tested in SCA3 patients) are not used in the clinic for other disorders

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All AEs will be followed up until resolution or stabilisation as judged by gynaecologist or paediatrician (site investigator) and the principal investigator