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These effects were more noticeable in longer trials and when ALA was combined with dietary changes.29 A 2020 dose-response meta-analysis confirmed small but statistically significant reductions in weight and BMI across 18+ randomized controlled trials.30 However, waist circumference (WC) a marker of central obesity showed no consistent change, and the benefit appeared greater in women and with longer treatment durations

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This study aimed to determine the appropriate dosing regimen for this patient population, ensuring both efficacy and tolerability 142

Chemical structures of lycii fructus polysaccharides tailored the gut microbiota composition of aged Caenorhabditis elegans