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Application of antioxidants in targeting ROS and clinical limitations Reducing ROS levels in the TME can have varied effects on T cells and tumor cells [123]

These morphological improvements are further supported by the histomorphometric data presented in Fig

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The authors concluded that, since the rate of postoperative side effects of fundoplication is low, while objective evidence of postoperatively de novo onset of GER occurred frequently, the addition of a fundoplication should be recommended during PEH repair