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Multiple sclerosis and infection: history, EBV, and the search for mechanism

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(1999) published that aberrant hypermethylation of the TSG p16, the putative metastasis suppressor gene death-associated protein kinase (DAPK), GSTP1, and the DNA repair gene O6-methylguanine-DNA-methyltransferase (MGMT) is observed in non-small cell lung cancer (NSCLC) tumors but not in any paired normal lung tissue

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showed that NAC safely improves lupus disease activity by blocking mTOR in T lymphocytes in SLE patients [137]