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Moreover, long-term safety and toxicity data for polyphenols & flavonoids-loaded nanocarriers are still sparse

First, phase II clinical trials evaluating MOTS-c in type 2 diabetes and sarcopenia are in development, and their results will provide the first randomized controlled evidence in humans to define therapeutic doses with statistical rigor

This pro-angiogenic activity, mediated at least in part through upregulation of VEGF receptor expression, is considered a key contributor to the accelerated tissue repair seen across different injury models

Cell 6 , 331343 (1975)

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