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Topical prescription agents such as hydroquinone, retinoids, azelaic acid, or tranexamic acid are applied directly to affected areas and are used under medical supervision to influence pigment production and skin renewal processes

For comparison with leaching of molecular dye, similar PLGA nanoparticles were loaded with Nile red, a popular dye used for labeling PLGA and other polymers 50 , and found to leach 32.2 6.7% of initial load after only 6 hrs

Wrote or contributed to the writing of the manuscript : Phillip M

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The solution to the instability problem of traditional peptides is peptide modification, which allows obtaining stable and effective peptide forms in the form of analogs