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Monitoring: Regular colonoscopies, blood tests, and imaging are important for monitoring disease activity, medication safety, and cancer surveillance (long-standing Crohns colitis increases colorectal cancer risk)

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Additionally, dietary supplements in the United States are not regulated the same way as food products are

Because B12 is water soluble, the body doesnt store large amounts of it long-term the way it stores fat-soluble vitamins, which is one reason ongoing dietary intake or supplementation matters for some people more than others

Unlike larger peptides, this small molecule can rapidly traverse the lipid bilayer of adipocytes to engage its intracellular target