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A membrane-free gut-on-chip study revealed that candidalysin disrupts tight junction proteins (ZO-1, occludin) to induce leaky gut, and further induces intestinal epithelial cells (IECs) apoptosis and necroptosis, thereby exacerbating barrier breakdown 111

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Addressing the clinical effects of L-carnitine at the intraovarian level presents challenges due to the intricate cellular and molecular aspects of PCOS, highlighting the need for further research to comprehend its clinical mechanisms across diverse patient populations, including those with PCOS, and to potentially discover new applications for ovarian dysfunctions associated with redox imbalance