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Temperature fluctuations, light exposure, or contamination can shorten effective life significantly

When you come off, you're not fighting metabolic adaptation as severely

Kittens with the following health issues may benefit from a B12 injection as one part of their supportive care plan: Gastrointestinal distress Malabsorption Inappetance Diarrhea Constipation Lethargy Weight loss Vomiting Anemia FIP Panleukopenia While B12 alone cannot resolve these issues, it can play a role in supporting the kittens gastrointestinal and immune health throughout their treatment and recovery

One study found that people who got a lot of B12 from their diet were more likely to get lung cancer

If you have been getting shots for several weeks and feel no difference at all, that is worth a conversation with your provider