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Recent evidence that pharmacological inhibition of the proteasome can be efficacious in the treatment of human cancers has set the stage for attempts to selectively inhibit the activities of disease-specific components of the UPS

Immunoreactive signals were formulated using an enhanced chemiluminescence kit (Biosharp, China) and visualized using a ChemiDoc MP system

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No increase was found for other types of cataract in these eyes, which is consistent with the idea that the nucleus is at particular risk from increased exposure to oxygen

Whether more frequent or less frequent administration would be more effective remains unknown