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Keywords: Obesity, Type 2 diabetes, GLP-1RA, Incretin therapy, Pharmacotherapy for obesity, Weight management, GLP1/GIP dual agonists, GLP-1/Glucagon dual agonists, GLP1/GIP/Glucagon triple agonists, Metabolism, Energy expenditure, Insulin secretion Introduction Obesity and type 2 diabetes (T2DM) are two of the most common noncommunicable diseases (NCDs) in the world
The small molecule ligand was processed using AutoDockTools 1.5.7 software, including adding hydrogen bonds and assigning proper torsion angles to chemical bonds, and then exported in PDBQT format
once reconstituted, refrigerate at 2-8C and use within 4-6 weeks
These technologies could transform compounds like GHK-Cu, which are effective locally but limited by short systemic half-lives, into practical therapeutic tools
Physical Activity: Gentle stretching and moderate exercise can help maintain muscle health and reduce stiffness
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