And I wish it was as easy as saying You should use this much and calling it a day
(The 503A Bulks List is a list of drug substances that the FDA has approved for compounding under section 503A of the Federal Food, Drug, and Cosmetic Act.) If the peptides meet the safety requirements, the committee will recommend reclassifying them onto this list, so they can then be legally prescribed and compounded
Mechanism of Action Inhibits Nicotinamide N-Methyltransferase (NNMT) Increases intracellular nicotinamide and NAD levels Improves mitochondrial efficiency and energy metabolism Supports lipolysis and fat oxidation Reduces adipocyte (fat cell) growth and proliferation Modulates inflammatory pathways and insulin signaling These effects may lead to enhanced fat metabolism, better blood sugar regulation, improved endurance, and a general increase in metabolic flexibility
Regular monitoring helps ensure the frequency remains appropriate Once levels stabilise, injections are usually spaced further apart, often every few months
Fat metabolism & fat storage Investigated in preclinical research as an NNMT inhibitor for how it affects fat cell metabolism and lipid storage
