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The TGF-/SMAD pathway is critical in regulating fibroblast activity, promoting extracellular matrix deposition by upregulating the production of collagen, fibronectin, and proteoglycans

Collagen strengthens your skin - It improves elasticity, hydration, and firmness, helping reduce fine lines and sagging

Research has shown GHK-Cu influences expression of over 4,000 human genes, stimulates collagen I, III and elastin synthesis, activates matrix metalloproteinases for extracellular matrix remodelling, supports angiogenesis through VEGF and FGF upregulation, and suppresses pro-inflammatory TNF- signalling

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