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The macrophage membrane allows the biomimetic MNP robots to carry cytokine receptors and capture specific cytokines as they self-propel at the lesion site

Epithalon is a synthetic tetrapeptide with the following amino acid makeup: alanine, glutamic acid, aspartic acid, and glycine

Even though this effect may be mediated by the insulin receptor, experimental KO mice for the insulin receptor gene show a potent glucose lowering effect of IGF-1, indicative that the hypoglycaemic effect is also mediated, in part, by its own IGF-1R

The peptides dual mechanism of simultaneously enhancing lipolysis and inhibiting lipogenesis creates optimal metabolic conditions for fat loss while preserving lean tissue

PLoS ONE 11 , e0151083 (2016)