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The number of puffs of a 3mg vape needed to match a cigarette can vary depending on factors such as the size of the cigarette and individual smoking habits

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After a few seconds, you will have to exhale the vapour, forming a cloud that is similar to cigarette smoke

7.2c Varenicline Varenicline is a partial agonist of the neuronal acetylcholine receptor subtype 42 and also functions as an agonist of dopamine turnover, ultimately reducing symptoms of nicotine withdrawal (87)

Is nicotine tolerance pharmacokinetic or pharmacodynamic in nature