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Long-term outcome of using allopurinol co-therapy as a strategy for overcoming thiopurine hepatotoxicity in treating inflammatory bowel disease

Notably, short-chain fatty acid (SCFA)-producing bacteria, especially butyrate producers like Roseburia and Faecalibacterium , are depleted (tofilov et al., 2022)

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[12] According to a patent, "Short duration safety studies with dihexa have uncovered no apparent toxicity

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