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This makes it distinct in research examining metabolic regulation pathways rather than direct supplementation strategies

Results observed in one study or experimental model should not be expected in every research setting

Because B12 is water-soluble, the NIH Office of Dietary Supplements notes that no tolerable upper intake level has been established excess B12 is excreted by the body rather than accumulating to toxic levels

[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Qiao A, Liang J, Ke Y, Li C, Cui Y, Shen L, et al

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