Likewise, a recently identified Th22 effector Th-cell cell subset, characterized by IL-22/13 production, has been implicated in psoriasis
Ann Clin Biochem Int J Biochem Lab Med 50:523545 Faghihi MA, Zhang M, Huang J, Modarresi F, Van der Brug MP, Nalls MA, Cookson MR, St-Laurent G 3rd, Wahlestedt C (2010) Evidence for natural antisense transcript-mediated inhibition of microRNA function
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Findings also suggest that postpartum depression, experienced by up to 15% of women [102], may also be linked to inflammation-induced KYN production [103]
In addition, those who have COMT Val/Val genotype (genotype with greater enzyme expression) were associated with a significantly increased risk of UF as compared to those with Val/Met genotype (intermediate expression) and Met/Met genotype (low expression), which could have explained the higher risk of UF in African American women (47% having Val/Val genotype) ( In vitro study showed that the ability of green tea extract in inhibiting the proliferation of leiomyoma cells is in part due to the potential of EGCG in reducing the expression of the COMT enzyme (Zhang et al., 2014)
